Cartan
§ 01 · AI-Native Arthroplasty
Cartan

Not AI-assisted.
Not AI-enabled.

Implant, instruments, and intelligence, co-designed from the ground up — an AI-native approach to total knee arthroplasty, beginning with the bicruciate-retaining knee.

Building digital twin…
Specimen · DU01
Natural Knee · CT 0.6 mm B31s
MR 1.5 T TrueFISP-3D · 2013-02-13
§ 02
Problem

The knee that patients prefer most
is the knee that surgeons use least.

A million Americans receive a new knee each year. Nearly all of them lose their anterior cruciate ligament — the structure that makes a knee feel like a knee. The bicruciate-retaining (BCR) procedure preserves it, along with the posterior cruciate. It is what patients want, and what surgeons can almost never deliver.

89%
of patients prefer a BCR knee to a cruciate-sacrificing one
74%
prefer BCR even over a cruciate-retaining (PCL-only) knee
<1%
of current total knee procedures actually use BCR
64%
of surgeons say BCR is clinically needed
§ 02.1
Why it hasn't worked

Three generations of bicruciate-retaining knees have tried, over fifty years. None have scaled. The failure mode is the same in every generation: BCR is so mechanically sensitive that the margin for surgical error is smaller than what conventional instrumentation can guarantee.

1972 – 2016
First-generation BCR

Multiple attempts across four decades. Ligament sparing was correct in principle; surgical precision was too manual to scale.

2016 – 2019
Zimmer Vanguard XP

Modern materials, conventional instrumentation. Withdrawn after three years — component placement tolerances could not be met consistently.

2018 – 2025
Smith+Nephew Journey II XR

The last available BCR in the U.S. Withdrawn December 2025 in portfolio rationalization. Zero BCR implants currently on market.

§ 02.2
Why it's hard
fig. 2.1 — crossed four-bar cruciate linkage

The knee is not a hinge. Its cruciate ligaments form a crossed four-bar linkage whose instantaneous center of rotation migrates through flexion — a polycentric motion with no single pivot to align to. Below: the same knee with the ACL preserved, and with it resected. The mathematics of alignment are different in the two cases.

ACL + PCL
Bicruciate retaining
PCL only
Conventional TKA (ACL resected)
0°
The cruciate ligaments form a crossed four-bar linkage (classically analyzed by Burmester, 1888; Menschik, 1974). The instantaneous center of rotation — the intersection of the ACL and PCL lines of action — traces an arc through flexion, producing the knee's polycentric motion and the subtle tibial internal rotation known as screw-home. Resect the ACL and the mechanism collapses to a single constraint: the pivot locks, the arc vanishes, the motion becomes a hinge.

BCR is so mechanically complex
it fundamentally requires AI to be performed reliably.

§ 03
Digital Twin

Every patient is different.
Every plan starts from the difference.

The implant is standardized. The surgeon is constant. The anatomy is not. Cartan begins each case from the patient's own scan — their own bone, their own ligament geometry, their own kinematics — and plans around them, not around an average.

Specimen · DU01
Natural Knee Dataset · drag to rotate
Select a patient

Six cadaveric knees from the University of Denver Natural Knee Dataset. Each one is its own patient; each one would need its own plan.

What Cartan builds from each scan
  • Bone and cartilage surfaces, from CT and MR, within the patient's coordinate frame.
  • Cruciate and collateral footprints — where the ligaments attach, not where they usually do.
  • A patient-specific kinematic model that drives the 50-year simulation, the surgical plan, and the intra-operative guidance.
§ 03.1
Data

The six specimens shown are a sample of the University of Denver Natural Knee Dataset (Rullkoetter, Laz, Shelburne et al.). On Cartan's production planner, the same pipeline runs from an incoming patient's MRI and CT — the digital twin is built from their scan, not selected from a library.

§ 04
Simulation
fig. 4.1 — tibiofemoral contact field

Fifty years of wear,
simulated before the first incision.

Cartan's digital twin exposes the long-horizon mechanics of a procedure before it happens. Contact pressure evolves as a scalar field on the tibial cartilage; wear, fracture, and loosening hazards accrue on parametric curves. The same patient, scrubbable across half a century.

Specimen · DU01 · tibial plateau
Cruciates preserved · focal stress on preserved bridge
Contact proximity
lowhigh
t =
0 yr
Peak tibial stress
18.4
MPa
-6.2 vs CR
15.035.0
Linear PE wear
0.000
mm
+0.000 vs CR
0.0000.300
Osseointegration
0
%
+0 vs CR
0100
Fracture risk
0.0
%
+0.0 vs CR
0.045.0
Loosening risk
0.0
%
+0.0 vs CR
0.045.0
§ 04.1
Survivorship
fig. 4.2 — % implants in situ, not revised
BCR at year 0
100.0%
vs CR
100.0%
0%100%

Curves are illustrative, tuned to published arthroplasty trends for readability — not clinical predictions. The same shape-space and simulation pipeline, driven by real patient-specific input, will feed Cartan's pre-operative planning interface.

§ 05
Surgery
fig. 5.1 — instantaneous helical axis sweep

Align the implant
to the patient's moving frame.

Chasles' theorem says every motion is a screw about an instantaneous axis. Sweep flexion and that axis traces a ruled surface — the axode — a compact signature of native knee motion. A faithful bicruciate-retaining procedure has to restore it. Not by matching surfaces: implant geometry and native anatomy obey different kinematic constraints, and the difficulty of mapping between them is exactly why BCR has historically failed to achieve mainstream utilization.

IHA sweep · 0° → 130° flexion
target axode · current · IHA
Alignment · RMS deviation
2.93°
Axes within tol.
2/5
Off target — significant deviation
Femoral flexiontarget 0.0°
0.0°+0.0°
Medial tibial slopetarget 5.0°
0.0°-5.0°
Lateral tibial slopetarget 3.0°
0.0°-3.0°
Coronal alignmenttarget -3.0°
0.0°+3.0°
Tibial rotationtarget 0.0°
0.0°+0.0°
§ 05.1
On the axode

At each instant during flexion, the tibiofemoral joint screws about a single line in space — its instantaneous helical axis. The one-parameter family of those lines sweeps a ruled surface: the axode.

Restoring the native axode with a bicruciate-retaining implant is not a resurfacing problem. The surfaces of the implant do not behave kinematically as the surfaces of the native joint; reproducing the shape of the knee does not reproduce its motion. The surgical plan has to solve the harder version — which is why BCR has resisted three generations of attempts, and why Cartan's planner is the first thing built around it.

§ 06
Post-Op
fig. 6.1 — latent-space flywheel

Every procedure
makes every future procedure better.

Each case Cartan runs leaves a trace. Pre-op imaging, the surgical plan, the intra-op execution, and the post-op outcome together place the patient in a learned latent space — a map of everyone Cartan has ever treated. As cases accumulate, the model's prediction for the next patient sharpens.

latent · Z₁latent · Z₂ ↑
excellentgoodfairpoorprediction errorn = 0model confidence · 0%
Cases enrolled
0/ 10,000
What tightens
  • Pre-operative outcome prediction for the next patient.
  • Alignment targets specific to each anatomical cluster.
  • Early detection of rare failure modes the first procedures never saw.
§ 06.1
PCCP

Cartan's platform is architected against the FDA's Predetermined Change Control Plan (PCCP) framework — the flywheel can keep turning without a new 510(k) each revolution. The axes shown here are synthetic; the structure is not.

· Build status
Phase 3 · Surgery + Post-Op online. Coming online next: Vision (roadmap), Team, Ask, and gated investor appendices.